Pathology and Laboratory Medicine (PaLM)

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The Pathology and Laboratory Medicine (PaLM) domain of IHE becomes active as of January 2016. This domain merges and supersedes the two prior domains Laboratory (LAB) and Anatomic Pathology (AP) respectively launched in 2003 and 2006. The main reason for this merger was the recognition of a significant amount of similarities of the two prior domains scopes, and a long practice of reuse of assets (content modules, transactions) and common thinking from one another. The decision for this merger has been prepared collectively along year 2015 by the LAB and AP leaderships, common secretariat and memberships, and was approved by the Board of IHE International on November 12, 2015.


The PaLM domain covers:

  • the representation and exchange of digital structured data, digital documents, digital images related to ordering, scheduling, performing and reporting diagnostic observations on in-vitro specimens collected from a patient or a non-living subject ;
  • the representation and exchange of digital structured data related to specimen management (preparation, transportation, handoff, aliquoting, storage, retrieval)
  • the secondary use and exchange of the observation results
  • the diagnostic storage and reuse of specimens in bio banks

when a pathology laboratory is involved and in charge of the production of the observation report following the diagnostic/prognostic/screening tests, this laboratory having at least one of the specialties listed below:

Laboratory specialty Sub-specialties
anatomic pathology specialties surgical pathology, autopsy, cytopathology, image cytometry, immunohistochemistry
clinical pathology specialties clinical chemistry, hematology, coagulation, blood gas, microbiology, immunology (allergy, auto-immunity, serology), transfusion medicine (blood bank testing), transplant compatibility testing (HLA), fertility, assisted medical procreation, cytogenetic (karyotype, molecular cytogenetic), drug monitoring and toxicology, flow cytometry
molecular pathology specialties gene mutations detection in tumor cells, genetic identification and characterization of infectious agents, diagnostic of genetic disorders

As of 2017, the scope of the PaLM domain also covers the transfusion medicine workflows.


The current sponsors of the PaLM domain are:

In their first years of existence the prior domains LAB and/or AP were also sponsored by GMSIH, ADICAP,SEIS, SEAP, SFIL and IHE Japan, ASIP Santé.

Current leadership

  • Planning co-chairs: Raj Dash, MD - FCAP ; Riki Merrick - Vernetzt
  • Technical co-chairs: Alesandro Sulis (CRS4) ; Kenichi Takahashi - Hitachi Hightech
  • Secretary and Board representative: Mary Kennedy - CAP

Quick links

Overview of the PaLM profiles

PaLM profiles usage.png

[Brief descriptions of the PaLM profiles]

IT Systems that can leverage PaLM profiles

Non-comprehensive list:

  • EHR-S in hospital and ambulatory care settings.
  • clinical and/or anatomic pathology laboratory information systems (LIS)
  • public health information systems and public health lab information systems
  • transfusion medicine systems
  • electronic healthcare record shared infrastructures (PHR, HIE …)
  • robotic specimen container distributers
  • barcode labelers
  • robotic specimen transportation systems
  • robotic peri-analytical devices in the laboratory work area
  • IVD analyzers in laboratory or on the point of care
  • middleware systems handling a set of analyzers and/or of peri-analytical devices, in laboratory or on the point of care.
  • imaging modalities
  • PACS and digital archive systems
  • biobank management systems

Guidance material and tools

Timeline: 2023 Planning and Development Cycle

Overall publication schedule: See the 2023 development cycle for PaLM
The following table outlines the activities of the domain planned for the 2023 year.

Timeframe Activity Scheduled Location
Production of new items
November 15 2022 Proposals of new work items Start of period for submission of new item proposals email to
December 12 2022 Proposals of new work items Closing of period for submission of new item proposals
January 11 2023 Decision for proposals of new work items finalized on call
Aug 2 Digital Pathology - Ordering & Reporting (DPOR) End of public comment period for Digital Pathology - Ordering & Reporting (DPOR) supplement for public comment email to Mary Jungers
Oct 1 Digital Pathology - Ordering & Reporting (DPOR) Request for publication of Digital Pathology - Ordering & Reporting (DPOR) supplement for Trial Implementation email to Mary Jungers
June 15 Technical Framework Request for publication of Techincal Framework to accommodate Change Requests email to Mary Jungers
Maintenance of PaLM TF
Year long Change proposal process email to Mary Jungers
March 6-10, 2023 NA Connectathon Austin, Texas
September 25-29, 2023 EU Connectathon Rennes, France
Year long Conference calls 2nd Wednesday of each month 8-10 am (CET), 1st hour: planning & mgmt, 2nd hour: technical conf calls + Zoom
June 13 - 14 PaLM Committee Face to face European Congress Of Digital Pathology Location Budapest, Hungary

Current Activity

  • Digital Pathology (DP) Profiles - Providing interoperability for solutions in support of a digital pathology workflow.
    • IHE PALM's Digital Pathology vision is captured in this article:
    • Digital Pathology Image Acquisition Profile: <add wiki page from template>
    • Digital Pathology Ordering & Reporting (DPOR) Profile: <add wiki page from template>

Published Profile links:

How to Participate

As a Laboratorian, Pathologist, or Advocate

Get involved in the planning committee. This is where the clinical problems are discussed and prioritized. The planning committee is an open group and is interested in having your input. Bring us your interoperability problems. You can also help by participating in the HIMSS showcase scenario definitions.

You can do this by:

  1. Becoming a IHE Member Organization
  2. Request to join our IHE PaLM Google Group
  3. Attend telephone conferences and face to face meetings
  4. Submit new profile proposals

As a Health IT Implementer

Get involved in the technical committee. Help make sure profiles are feasible and will work for you. Implement the profile, and come experience the IHE Connectathon event. 2011 Connectathon video clip

As a Health IT Buyer

In addition to getting involved in the planning committee, hold your vendors accountable. Put a statement in your RFP that indicates you want the vendor to support the actor in the profile you desire.

Demonstrations & Presentations

The following are recent and upcoming public presentations and demonstrations about IHE Lab. Email our IHE PaLM Google Group about presentations or demonstrations you know about.

Date Location Event Details

Standards Organization - Professional Meetings/Conferences

Date Organization Location More Information
Jan 16-20, 2023 HL7 WGM Las Vega Resort, Henderson, NV
May 8 -12, 2023 HL7 WGM New Orleans, LA
June 14 - 17 2023 European Congress on Digital Pathology (ECDP 2023) Catania, Italy
TBD in Sep 2023 HL7 WGM TBD
October 26-27, 2023 SNOMED CT Expo Atlanta, Georgia, USA (and online)

See Also


Mailing Lists

Milestones for all IHE domains

Standard Organizations Link List

This page is based on the Domain Template.